Aug 29, - The mild side effects of isotretinoin can include: dry skin. chapped lips. dry eyes. dry nose that may lead to nosebleeds. Oct 21, - Is having a dry throat a symptom of accutane? Seems like I've had a cough ever since I started taking this dru By sean j in Prescription acne Accutane and Sore Throat. Jun 18, - The side effect I was most afraid of was depression: some Accutane users My lips either feel like they have a weird extra layer of dry skin over. My Accutane Journey: Clearing my Acne + Eyesight Side Effects I do not wake up with a dry mouth so im not sleeping with my mouth What to consider before using this medicine? Posted April 4, Learn what to do about acne when it shows up on your temples. I senced a tickle inside my lips 4 times in 11 months.